2007.09-2011.07 浙江大学
2011.09-2016.10中国科学院上海有机所生物与化学交叉研究中心

自吞噬（autophagy），细胞程序性坏死(necroptosis)

Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J. (2018) TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. Sep 6;174(6):1477-1491.

Li F, Xu D, Wang Y, Zhou Z, Liu J, Hu S, Gong Y, Yuan J, Pan L. (2018) Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. Autophagy. 14(1):66-79.

Xu D, Liu J, Fu T, Shan B, Qian L, Pan L, Yuan J. (2017) USP25 regulates Wnt signaling by controlling the stability of tankyrases. Genes Dev.31(10):1024-1035.

Xu D, Shan B, Sun H, Xiao J, Zhu K, Xie X, Li X, Liang W, Lu X, Qian L, Yuan, J. (2016) USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1. Genes Dev, 30(15):1718-30.

Xu D, Shan B, Lee BH, Zhu K, Zhang T, Sun H, Liu M, Shi L, Liang W, Qian L, Xiao J, Wang L, Pan L, Finley D &Yuan J. (2015). Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. Elife, 4:e10510.

Xu D, Zhang T, Xiao J, Zhu K, Wei R, Wu Z, Meng H, Li Y&Yuan J.(2015) Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy, 11(4):617-28.

Zhang T, Dong K#, Liang W#, Xu D#, Xia H#, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, Qi C, Zhang Q, Sun A, Lipinski M, Zhu H, Xiong Y, Pandolfi PP, Li H, Yu Q& Yuan J. (2015) G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. Elife, 4:e06734. (#co-second author)

Xiao J, Zhang T#, Xu D#, Wang H, Cai Y, Jin T, Liu M, Jin M, Wu K&Yuan J. (2015) FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. Genes Dev, 29(2):184-96. (#co-second author)

Xu D, Lu C, &ChenW. (2012). Palladium-catalyzed double arylations of terminal olefins in acetic acid. Tetrahedron, 68(5):1466-74.

Gu S, Xu D, &ChenW. (2011). Heterobimetallic complexes containing an N-heterocyclic carbene based multidentate ligand and catalyzed tandem click/Sonogashira reactions. Dalton Trans, 40(7):1576-83.

Liu B, Zhang Y, Xu D, & Chen W. (2011).Facile synthesis of metal N-heterocyclic carbene complexes. ChemComm, 47(10):2883-85.