1. Hu, Z.#; Chen, P.#; Li, W.; Douglas, T.; Hines, J.; Liu, Y.; Crews, C.; Targeted Dephosphorylation of Tau by Phosphorylation Targeting Chimeras (PhosTACs) as a Therapeutic Modality. Journal of the American Chemical Society. 2023, 145, 7, 4045–4055
2. Zhang, S.#; Hu, Z.#; Tanji, H.; Jiang, S.; Das, N.; Li, J.; Sakaniwa, K.; Jin, J.; Bian, Y.; Ohto, U.; Shimizu, T.; Yin, H.; Inhibition of Toll-like Receptor 8 through stabilization of its resting state. Nature Chemical Biology. 2018, 14, 58-64 (cover article)
3. Hu, Z.; Tanji, H.; Koo, K.; Chan, J.; Zhang, S.; Candia, A.; Shimizu, T.; Yin, H.; Small-molecule TLR8 antagonists via structure-based rational design. Cell Chemical Biology. 2018, 25, 1286–1291 (cover article)
4. Hu, Z.; Crews, C.; Recent Developments in PROTAC-Mediated Protein Degradation: From Bench to Clinic. Chembiochem. 2022, 23 (2), e202100270.
5. Chen, P. #; Hu, Z. #; An, E.; Okeke, I.; Zheng, S.; Lo, X.; Gong, A.; Jaime-Figueroa, S.; Crews, C.; Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). ACS Chemical Biology. 2021, 16, 12, 2808–2815.
6. Hu, Z.; Zhang, T.; Jiang, S.; Yin, H.; Protocol for evaluation and validation of TLR8 antagonists in HEK-Blue cells via secreted embryonic alkaline phosphatase assay. Cell Star Protocols. 2022,3, 101061.
7. Samarasinghe, K.; Jaime-Figueroa, S.; Burgess, M.; Nalawansha, D.; Dai, K.; Hu, Z.; Bebenek, A.; Holley, S.; Crews, C.; Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras. Cell Chemical Biology. 2021, 28(5): 648-661 e645.
8. Hany, Z.; Meas, H.; Haug, M.; Beckwith, M.; Louet, C.; Ryan, L.; Hu, Z.; Landskron, J.; Nordbo, S.; Tasken, K,; Yin, H.; Damas, J.; Flo. T.; Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. Nature Communication. 2020 Jan 9;11(1):147
9. Xia, T.; Hu, Z.; Ji, W.; Zhang, S.; Shi, H.; Liu, C.; Pang, B.; Liu, G.; Liao, X.; Synthesis of Withasomnine and Pyrazole derivatives via intramolecular dehydrogenative cyclization, as well as biological evaluation of Withasomnine-based scaffolds. Organic Chemistry Frontiers. 2018,5, 850-854
10. Moen,S.; Ehrnstrom, B.; Kojen, J.; Yurchenko, Beckwith, K.; Afset, J.; Damas,J.; Hu, Z.; Yin, H.; Espevik, T.; Stenvik, J.; Human Toll-like Receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontier in Immunology.10:1209.
11. Ehrnstrom, B.; Kojen, J.F.; Moen, S.H.; Hu, Z.; Damas, J.K., Mollnes, T.E.; Yin, H.; Espevik, T.; Stenvik J.; TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology 2020, 107, 673–683.
12. Chen, H.#; Hu, Z.#; Tang, C.; Quinn, R.; Feng, Y.; Yao, S.; Ye Y.; Dictamins A–C, three unprecedented apotirucallane-type trinortriterpenoids from Dictamnus dasycarpus.Tetrahedron Letters. 2013, 5, 4150–4153
13. Qi X.; Wang, L.; Zhu, J.; Hu, Z.; Zhang, J.; Self-double-emulsifying drug delivery system (SDEDDS): A new way for oral delivery of drugs with high solubility and low permeability. International Journal of Pharmaceutics. 2011, 409, 245–251.
# Co-First Author.
